Official Journal Health Science of Prince of Songkla University

  • Home
  • Search
  • Current
  • Archives
  • Announcements
  • Guide for Authors
  • Publication Ethics
  • Editorial Board
  • Submit
  • About
  • Contact
  • Online-first Articles
  • EVENTS
  • Review Process
  • Policies
Home > Online-first > Vuttanon
Cover Image

Burden and Quality of Life in Prostate Cancer Caregivers

Nuttamon Vuttanon, Chutima Meechamnan, Lalida Noppakun, Srisuda Iamruksa, Jakkapob Dhatsuwan, Supon Sriplakich, Maneewan Wiratkasem

Abstract

Objective: Caregivers of patients with metastatic prostate cancer often face physical and emotional strain. Guided by the Informal Caregiving Integrative Model (ICIM), this study aimed to identify factors predicting reported caregiving burden and its impact on quality of life (QoL) among Thai caregivers.
Material and Methods: This cross-sectional correlational study involved 116 caregivers at a Thai university hospital. Data were collected via interviewer-administered questionnaires, including the Zarit Burden Interview and the WHOQOL-BREF. Analysis included descriptive statistics, Spearman correlation, and logistic regression.
Results: Caregivers reported a low average burden score (median = 3.00, IQR = 13.00) and a high level of QoL (mean = 99.35, SD = 9.13). Binary logistic regression analysis revealed that caregiver health status, patient symptom intensity, and illness duration were significant determinants of caregiving burden (p < 0.05), with a high predictive accuracy of 88.8%. The model also identified caregiver education level, patient illness duration, and reported caregiving burden as significant predictors of QoL, achieving a predictive accuracy of 81.9%.
Conclusion: The findings suggest that caregiver characteristics and clinical factors influence reported burden and QoL. In the Thai context, family support and cultural values likely mitigate perceived strain. Careful interpretation of these reported scores is recommended due to the potential social desirability bias. Healthcare providers should prioritize caregiver health and provide disease-specific guidance to sustain high QoL for both caregivers and patients.

 

 Keywords

Caregiver burden; quality of life; metastatic prostate cancer; Family caregivers; determinants; nursing care

 Full Text:

PDF (Early Version)

References

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68:394-424.

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2021;71:209-249.

National Cancer Institute, Ministry of Public Health. Hospital-based cancer registry 2017. Bangkok: Ministry of Public Health; 2017.

Lojanapiwat B. Urologic cancer in Thailand. Jpn J Clin Oncol. 2015;45(11):1007-1015.

European Association of Urology. EAU guidelines on prostate cancer [Internet]. Arnhem: European Association of Urology; 2021 [cited 2021 Apr 9]. Available from: https://uroweb.org/guidelines/archive/prostate-cancer

National Cancer Institute, Ministry of Public Health. Guidelines for screening, diagnosis, and treatment of prostate cancer. Bangkok: Kosit Printing; 2017.

Schwartz K, Beebe-Dimmer J, Hastert TA, Ruterbusch JJ, Manty J, Harper F, et al. Caregiving burden among informal caregivers of African Americans. J Cancer Surviv. 2021;15:630-40.

Bevans MF, Sternberg EM. Caregiving burden, stress, and health effects among family caregivers of adult cancer patients. JAMA. 2012;307(4):398-403.

Ayumi T, Sena Y, Harue A. Caregiver burden of cancer patients related to cognitive decline at end of life. Cancer Care Res Online. 2022;2(1):e105.

Adelman RD, Tmanova LL, Delgado D, Dion S, Lachs MS. Caregiver burden: a clinical review. JAMA. 2014;311(10):1052-1060.

Shin JY, Lim JW, Shim D, Park SM, Yang HK, Kim SY, et al. Underestimated caregiver burden by cancer patients and its association with quality of life, depression, and anxiety among caregivers. Eur J Cancer Care (Engl) 2018;27e12814.

Langenberg SMCH, van Herpen CML, van Opstal CCM, van der Graaf WTA, Prins JB, van Laarhoven HWM. Caregivers’ burden and fatigue during and after patients’ treatment with concomitant chemoradiotherapy for locally advanced head and neck cancer: a prospective observational pilot study. Support Care Cancer 2019;27:4145-54.

Gerain P, Zech E. Informal caregiver burnout? Development of a theoretical framework to understand the impact of caregiving. Front Psychol. 2019;10:1748.

Toonsiri C, Sunsern R, Lawang W. Development of the Burden Interview for caregivers of patients with chronic illness. J Nurs Sci Educ 2011;34:62-75.

Mahattanirunkul S, Tantipiwattanasakul W, Phumpaisanchai W. World Health Organization quality of life indicators: Thai version [Internet]. Nonthaburi: Department of Mental Health; 2002 [cited 2020 May 5]. Available from: https://www.dmh.go.th/test/download/files/whoqol

Lunpilar C. Factors related to burden of caregivers for the elderly bed bound in Muang District, Mahasarakham. Mahasarakham Hosp J 2021;18:33-43.

Fellia T, Sarafis P, Bouletis A, Tzenetidis V, Papathanasiou I, Apostolidi TP, et al. Correlation of cancer caregiver’s burden, stress, and their quality of life. Adv Exp Med Biol. 2023;1425:267-73.

Suksathapornlert P, Tanthapong U, Srijongjai S. Caregiving burden factors affecting quality of life among cancer end-stage patients in Nakhonpathom Province. Christian University of Thailand Journal. 2014;20(3):493-509.

Noppakun L, Indratula R, Vuttanon N. Quality of life among persons with prostate cancer. Srinagarind Med J 2020;35:320-5.

Moghaddam ZK, Rostami M, Zeraatchi A, Bytamar JM, Saed O, Zenozian S. Caregiving burden, depression, and anxiety among family caregivers of patients with cancer: an investigation of patient and caregiver factors. Front Psychol. 2023;14:1059605.

Kahriman F, Zaybak A. Caregiver burden and perceived social support among caregivers of patients with cancer. Asian Pac J Cancer Prev. 2015;16:3313-7.

Geng HM, Chuang DM, Yang F, Yang Y, Liu WM, Liu LH, et al. Prevalence and determinants of depression in caregivers of cancer patients: a systematic review and meta-analysis. Medicine (Baltimore). 2018;97(39):e11863.

Al Ali NM, Eid A, Aljada N. Determinants of quality of life in family caregivers of patients with leukemia: a cross-sectional study. SAGE Open. 2023;13:21582440231205350.

Afzal MI, Lijuang W. Determinants of caregivers’ burden of cancer patients: a systematic review. In: Sarginson WP, Ashar MN, Maureen I, editors. Reimagining Innovation in Education and Social Science. London: Routledge; 2023. p. 305-14.

Songsangchan C, Thanasilp S, Pudtong N. Factors predicting quality of life in family caregivers of terminal cancer patients. RTN Med J. 2017;44(2):111-30.

Rooeintan M, Haghighi S, Ahmadi M. Caregiver burden and quality of life among caregivers of cancer patients in Ahvaz, 2021-2022: a cross-sectional study. Jundishapur J Chronic Dis Care. 2023;12(4):e138098.

Valluri V. Assessment of quality of life of caregivers of persons living with cancers: a tertiary health center-based cross-sectional study. Qeios [Internet]. 2023 [cited 2023 Dec 1]. Available from: https://doi.org/10.32388/4AMYHD.2

Akter J, Konlan KD, Nesa M. Factors influencing cancer patients’ caregivers’ burden and quality of life: an integrative review. Heliyon 2023;9(11):e21243.

DOI: http://dx.doi.org/10.31584/jhsmr.20261503

Refbacks

  • There are currently no refbacks.
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

SUBMIT A PAPER

JHSMR accepts online submission through

AHR-iCON 2026

About The Authors

Nuttamon Vuttanon
Faculty of Nursing, Nation University, Chiang Mai campus, San Sai, Chiang Mai 50210,
Thailand

Chutima Meechamnan
Faculty of Nursing, Chiang Mai University, Mueang Chiang Mai, Chiang Mai 50200,
Thailand

Lalida Noppakun
Faculty of Nursing, Chiang Mai University, Mueang Chiang Mai, Chiang Mai 50200,
Thailand

Srisuda Iamruksa
Faculty of Nursing, Chiang Mai University, Mueang Chiang Mai, Chiang Mai 50200,
Thailand

Jakkapob Dhatsuwan
Faculty of Nursing, Chiang Mai University, Mueang Chiang Mai, Chiang Mai 50200,
Thailand

Supon Sriplakich
Faculty of Medicine, Chiang Mai University, Mueang Chiang Mai, Chiang Mai 50200,
Thailand

Maneewan Wiratkasem
Faculty of Medicine, Chiang Mai University, Mueang Chiang Mai, Chiang Mai 50200,
Thailand

Article Tools
Abstract
Print this article
Indexing metadata
How to cite item
Email this article (Login required)
Email the author (Login required)

Journal Metrics

2023 (June)
Acceptance rate: 23.6%
2024 (June)
Acceptance rate: 19%
2025 (June)
Acceptance rate: 23%



Submission to final decision
74 days

Acceptance to publication
40 days


CiteScore Rank 2025

0.7
2025
CiteScore
 
32nd percentile
Q 3

JHSMR Facebook

JHSMR Facebook

Supported by

 

JHSMR now Indexed in








Image result for crossref





PSUMJ Homepage

Keywords COVID-19 SARS-CoV-2 Thailand Vietnam children depression diabetes diabetes mellitus elderly hypertension knowledge mental health mortality older adults prevalence public health quality of life reliability risk factors treatment validity
Journal Content

Browse
  • By Issue
  • By Author
  • By Title
Font Size

Open Journal Systems