Bovine Pericardium Membrane as a Barrier Material for Periodontal Tissue Regeneration: A Retrospective Study
Abstract
Objective: This study aimed to evaluate the efficacy of bovine pericardium as a barrier membrane for guided periodontal tissue regeneration.
Material and Methods: The records of 20 periodontitis patients with a median age of 44.50 (IQR17) who underwent guided tissue regeneration (GTR) using bovine pericardium membranes (PericardLEMB, Tissue Bank, USM, Malaysia) were retrieved. The parameters, including plaque score (PS), gingivitis score (GS), probing pocket depth (PPD), clinical attachment loss (CAL), and alveolar bone loss from pre- to post-6-months of GTR, were compared using the Wilcoxon Paired Signed-Ranks test.
Results: We found statistically significant improvements in all of the parameters 6 months post-GTR (p-value<0.05). The median and interquartile range (IQR) for PS and GS decreased from 20.68% (IQR18.60) to 12.62% (IQR11.10) and 25.90% (IQR25.58) to 10% (IQR17.73), respectively. Similarly, after 6 months, median PPD and CAL had decreased to 3.25mm (IQR1.56) and 3.25mm (IQR1.92), respectively, from the baseline values of 7.00mm (IQR3.38) and 7.50mm (IQR3.61). Consistently, significant radiographic alveolar bone gain (20%) was observed 6 months after GTR.
Conclusion: Despite this study’s limitations, such as small sample size, lack of control group, and short follow-up duration, it is conceivable to propose that utilizing BPM as bioabsorbable barrier membranes in the GTR procedure promotes periodontal tissue regeneration.
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