Prescription Patterns of Antibiotics, Nonsteroidal Anti-Inflammatory Drugs, and Anti-ulcer Drugs: A Prospective Cross-Sectional Observational Study
Abstract
Objective: The study of prescription patterns of antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), and anti-ulcer drugs is crucial, as these combinations are widely used in managing diseases with overlapping needs. In infections with inflammatory components, these drugs treat infection, pain, and inflammation. Post-surgical care uses them to prevent infections, manage pain, and reduce NSAID-induced gastrointestinal risks. In chronic conditions like arthritis, long-term NSAIDs and infections require anti-ulcer drugs to prevent complications. Studying these patterns ensures rational use and minimizes risks. Analyzing these patterns ensures rational use, minimizes adverse effects, and optimizes therapeutic outcomes.
Material and Methods: One hundred prescriptions were analyzed, documenting patient demographics, diagnosis, drug regimens, and prescribing patterns within 6 months.
Result: Among 29 antibiotics, 71% were prescribed in combination therapy, with 64.98% via the intravenous (IV) route. Ceftriaxone 1000 mg was the most common dose (65%) and the most prescribed antibiotic (37.57%). Seven NSAIDs were mainly prescribed as monotherapy (79%) and orally (89.06%), with paracetamol, 650mg, being the most common (39.84%). Eight anti-ulcer drugs were mostly monotherapy (89%), often IV for proton pump inhibitors (PPIs) (67.77%), with pantoprazole the most common (80.49%).
Conclusion: The study identified a predominance of male patients (41-50 years). Combination therapy and brand-name prescriptions were frequent for antibiotics, while NSAIDs and anti-ulcer drugs favoured monotherapy and brand names. IV administration was prevalent for antibiotics and anti-ulcer drugs, contrasting with oral NSAID administration. Ceftriaxone, paracetamol, and pantoprazole emerged as the most prescribed drugs in their respective categories.
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