The Role of Probiotics on Depression and Quality of Life in Irritable Bowel Syndrome Patients
Abstract
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by abdominal pain and/or constipation, often accompanied by altered stool frequency and shape. The gut microbiota, predominantly residing in the distal small and large intestines, comprises approximately 100 trillion microorganisms. Studies have identified a higher prevalence of Firmicutes (e.g., Lactobacillus, Ruminococcus), Proteobacteria, and Veillonella in IBS patients, alongside reduced populations of Lactobacillus and Bifidobacterium. Probiotics haves a role in alleviating IBS symptoms and depressive symptoms. Emerging evidence highlights the potential of probiotics to modulate the brain-gut axis, particularly in IBS patients with coexisting depressive symptoms, in order to alleviate IBS symptoms and depressive symptomps.
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