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COVID-19 Vaccine Acceptance Among Patients with Mental Illness: A Case-Control Study After the Pandemic

 
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1. Title Title of document COVID-19 Vaccine Acceptance Among Patients with Mental Illness: A Case-Control Study After the Pandemic
 
2. Creator Author's name, affiliation, country Wanmai Woonkaew; Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,; Thailand
 
2. Creator Author's name, affiliation, country Chonnakarn Jatchavala; Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,; Thailand
 
2. Creator Author's name, affiliation, country Tharntip Sangsuwan; Department of Family and Preventive Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,; Thailand
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) anxiety; COVID-19 vaccine booster; mental disorders; optimism; SARS-CoV-2
 
4. Description Abstract

Objective: To investigate the prevalence of anxiety, optimism, and coronavirus disease 2019 (COVID-19) vaccine acceptance among patients with mental illnesses in Southern Thailand in the period after the pandemic.
Material and Methods: A total of 160 outpatients, 80 with mental disorders and 80 age- and gender-matched individuals without mental disorders, participated in this study between August and November 2023. Data were collected using self-reported questionnaires on perception and personal experience of COVID-19 vaccination, including the Thai version of the COVID-19 Anxiety Scale.
Results: The psychiatric group had significantly higher rates of unemployment (p-value=0.02), residence in the armed-conflict areas of Southern Thailand (p-value=0.03), and self-payment for treatment (p-value=0.003) compared with the non-psychiatric group. A smaller proportion of patients in the psychiatric group had received full vaccination, including at least one booster dose (52.5%), compared with the control group (75.0%; p-value=0.005). Levels of optimism and anxiety toward COVID-19 infection were mostly moderate and not significantly different between the groups. Statistically, individuals with mental illnesses perceived the severity of COVID-19 2.4 times lower than those without (p LR test=0.016). Most participants in both groups were willing to receive the COVID-19 vaccine if advised by their psychiatrists (68.8%), family doctors (73.8%), pharmacists (63.7% and 70.0%), or village health volunteers (VHVs) (56.2%).
Conclusion: Psychiatric patients were more likely to be unemployed, live in armed-conflict areas, pay for their own medical care, and have lower vaccination rates. At the same time, optimism and anxiety levels were similar compared to those of non-psychiatric groups regarding COVID-19.
 
5. Publisher Organizing agency, location Faculty of Medicine, Prince of Songkla University
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 2026-06-02
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://www.jhsmr.org/index.php/jhsmr/article/view/1345
 
10. Identifier Digital Object Identifier (DOI) http://dx.doi.org/10.31584/jhsmr.20261345
 
11. Source Title; vol., no. (year) Journal of Health Science and Medical Research; Vol 44, No 5 (2026): Sep-Oct (Upcoming Issue)
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2026 Journal of Health Science and Medical Research Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.